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A chemical compound is a chemical substance composed of many identical (or ) containing from more than one held together by . A molecule consisting of atoms of only one element is therefore not a compound. A compound can be transformed into a different substance by a chemical reaction, which may involve interactions with other substances. In this process, bonds between atoms may be broken or new bonds formed or both.

There are four major types of compounds, distinguished by how the constituent atoms are bonded together. Molecular compounds are held together by ; are held together by ; intermetallic compounds are held together by ; coordination complexes are held together by coordinate covalent bonds. Non-stoichiometric compounds form a disputed marginal case.

A specifies the number of atoms of each element in a compound molecule, using the standard with numerical . Many chemical compounds have a unique identifier assigned by the Chemical Abstracts Service. Globally, more than 350,000 chemical compounds (including mixtures of chemicals) have been registered for production and use.


History of the concept

Robert Boyle
The term "compound"—with a meaning similar to the modern—has been used at least since 1661 when The Sceptical Chymist was published. In this book, Boyle variously used the terms "compound", "compounded body", "perfectly mixt body", and "concrete". "Perfectly mixt bodies" included for example gold, lead, mercury, and wine. While the distinction between compound and is not so clear, the distinction between and compound is a central theme.


Corpuscles of elements and compounds
Boyle used the concept of "corpuscles"—or "atomes", as he also called them—to explain how a limited number of elements could combine into a vast number of compounds:


Isaac Watts
In his Logick, published in 1724, the English minister and logician gave an early definition of chemical element, and contrasted element with chemical compound in clear, modern terms.


Definitions
Any substance consisting of two or more different types of () in a fixed proportion can be termed a chemical compound; the concept is most readily understood when considering pure chemical substances. It follows from their being composed of fixed proportions of two or more types of atoms that chemical compounds can be converted, via chemical reaction, into compounds or substances each having fewer atoms. A is a way of expressing information about the proportions of atoms that constitute a particular chemical compound, using for the chemical elements, and to indicate the number of atoms involved. For example, is composed of two bonded to one atom: the chemical formula is H2O. In the case of non-stoichiometric compounds, the proportions may be reproducible with regard to their preparation, and give fixed proportions of their component elements, but proportions that are not integral e.g.,. Phase diagram for Palladium-Hydrogen System

Chemical compounds have a unique and defined chemical structure held together in a defined spatial arrangement by . Chemical compounds can be compounds held together by , salts held together by , intermetallic compounds held together by , or the subset of chemical complexes that are held together by coordinate covalent bonds.

(2025). 9780716757016, W.H. Freeman. .
Pure are generally not considered chemical compounds, failing the two or more atom requirement, though they often consist of molecules composed of multiple atoms (such as in the diatomic molecule H2, or the polyatomic molecule S8, etc.). Many compounds have a unique numerical identifier assigned by the Chemical Abstracts Service (CAS): its .

There is varying and sometimes inconsistent nomenclature differentiating substances, which include truly non-stoichiometric examples, from chemical compounds, which require the fixed ratios. Many solid chemical substances—for example many —are chemical substances, but do not have simple formulae reflecting chemical bonding of elements to one another in fixed ratios; even so, these substances are often called "non-stoichiometric compounds". It may be argued that they are related to, rather than being chemical compounds, insofar as the variability in their compositions is often due to either the presence of foreign elements trapped within the crystal structure of an otherwise known true chemical compound, or due to perturbations in structure relative to the known compound that arise because of an excess or deficit of the constituent elements at places in its structure; such non-stoichiometric substances form most of the crust and mantle of the Earth. Other compounds regarded as chemically identical may have varying amounts of heavy or light of the constituent elements, which changes the ratio of elements by mass slightly.


Types

Molecules
A molecule is an electrically neutral group of two or more atoms held together by chemical bonds.
(1990). 9780395433027, Houghton Mifflin Co..
(2025). 9780130669971, . .
A molecule may be , that is, it consists of atoms of one chemical element, as with two atoms in the molecule (O2); or it may be , a chemical compound composed of more than one element, as with water (two hydrogen atoms and one oxygen atom; H2O). A molecule is the smallest unit of a substance that still carries all the physical and chemical properties of that substance.


Ionic compounds
An ionic compound is a chemical compound composed of held together by electrostatic forces termed . The compound is neutral overall, but consists of positively charged ions called and negatively charged ions called . These can be such as the (Na+) and (Cl) in , or species such as the () and () ions in ammonium carbonate. Individual ions within an ionic compound usually have multiple nearest neighbours, so are not considered to be part of molecules, but instead part of a continuous three-dimensional network, usually in a crystalline structure.

Ionic compounds containing basic ions like (OH) or (O2−) are classified as bases. Ionic compounds without these ions are also known as salts and can be formed by acid–base reactions. Ionic compounds can also be produced from their constituent ions by of their , precipitation, , a solid-state reaction, or the electron transfer reaction of reactive metals with reactive non-metals, such as gases.

Ionic compounds typically have high and , and are and . As solids they are almost always electrically insulating, but when or dissolved they become highly conductive, because the ions are mobilized.


Intermetallic compounds
An intermetallic compound is a type of that forms an ordered solid-state compound between two or more metallic elements. Intermetallics are generally hard and brittle, with good high-temperature mechanical properties.
(2015). 9781305076761, Cengage Learning.
(1997). 9780309524384, National Academies Press.
(2025). 9780824789008, Marcel Dekker.
They can be classified as stoichiometric or nonstoichiometric intermetallic compounds.


Complexes
A coordination complex consists of a central atom or ion, which is usually and is called the coordination centre, and a surrounding array of bound molecules or ions, that are in turn known as or complexing agents.
(2025). 9780470687123, Wiley.
Many metal-containing compounds, especially those of , are coordination complexes.


Bonding and forces
Compounds are held together through a variety of different types of bonding and forces. The differences in the types of bonds in compounds differ based on the types of elements present in the compound.

London dispersion forces, part of the Van der Waals force, are the weakest force of all intermolecular forces. They are temporary attractive forces that form when the in two adjacent atoms are positioned so that they create a temporary . London dispersion forces can create Van der Waals molecules. Additionally, they are responsible for condensing substances to liquids, and to further freeze to a solid state dependent on how low the temperature of the environment is.

A , also known as a molecular bond, involves the sharing of electrons between two atoms. Primarily, this type of bond occurs between elements that fall close to each other on the periodic table of elements, yet it is observed between some metals and nonmetals. This is due to the mechanism of this type of bond. Elements that fall close to each other on the periodic table tend to have similar electronegativities, which means they have a similar affinity for electrons. Since neither element has a stronger affinity to donate or gain electrons, it causes the elements to share electrons so both elements have a more stable .

occurs when valence electrons are completely transferred between elements. Opposite to covalent bonding, this chemical bond creates two oppositely charged ions. The metals in ionic bonding usually lose their valence electrons, becoming a positively charged . The nonmetal will gain the electrons from the metal, making the nonmetal a negatively charged . As outlined, ionic bonds occur between an electron donor, usually a metal, and an electron acceptor, which tends to be a nonmetal.

occurs when a bonded to an electronegative atom forms an connection with another electronegative atom through interacting dipoles or charges.


Reactions
A compound can be converted to a different chemical composition by interaction with a second chemical compound via a chemical reaction. In this process, bonds between atoms are broken in both of the interacting compounds, and then bonds are reformed so that new associations are made between atoms. Schematically, this reaction could be described as , where A, B, C, and D are each unique atoms; and AB, AD, CD, and CB are each unique compounds.


See also
  • Chemical structure
  • IUPAC nomenclature
  • Dictionary of chemical formulas
  • List of compounds


Sources

Further reading
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